Studies of acute and convalescent COVID-19 patients have observed that T cell responses are associated with reduced disease ( 5– 7), suggesting that SARS-CoV-2–specific CD4 + T cell and CD8 + T cell responses may be important for control and resolution of primary SARS-CoV-2 infection.
Humans make SARS-CoV-2–specific antibodies, CD4 + T cells, and CD8 + T cells in response to SARS-CoV-2 infection ( 1– 4). Smith, Daniela Weiskopf, Alessandro Sette, and Shane Crotty +18 authors +16 authors +11 authors fewer Authors Info & AffiliationsĬoronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a serious disease that has resulted in widespread global morbidity and mortality.
Rawlings, Bjoern Peters, Florian Krammer, Viviana Simon, Erica Ollmann Saphire, Davey M. Ramirez, Sonya Haupt, , April Frazier, Catherine Nakao, Vamseedhar Rayaprolu, Stephen A.
Dan, Jose Mateus, , Yu Kato, Kathryn M.
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